PRYOR, Circuit Judge:
The main issue presented in this appeal involves a jury instruction about proving a violation of the Controlled Substances Act, 21 U.S.C. § 801 et seq., by medical professionals. A physician, his assistant, and a pharmacist convicted of violating the Act in connection with the operation of a "pill mill" argue that a jury instruction at their trial ran afoul of the decision in Gonzales v. Oregon,
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