MATHEWS, Circuit Judge.
Petitioners seek review of an order issued by respondent under the Federal Food, Drug and Cosmetic Act, 21 U.S.C.A. §§ 301-392. Thereby respondent promulgated the following regulation (9 F.R. 11836, 21 C.F.R., 1944 Supp., § 120.1): "The quantity of fluorine remaining as insecticidal residue on apples and pears is hereby limited to not more that 7 milligrams of fluorine, calculated as F, per kilogram of each such fruit."
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